The Neurological Reasons Why People with OCD Can’t Simply Stop Compulsions

Mar 14, 2025
 | OCD

When someone has OCD, telling them to “just stop” their compulsions is not only unhelpful—it also ignores the underlying neurological reasons that make stopping so difficult. OCD is not about a lack of willpower; it is rooted in the brain, where specific patterns of activity and chemical imbalances drive the cycle of obsessions and compulsions.

Research shows that OCD involves heightened activity in certain brain regions, such as the orbitofrontal cortex, anterior cingulate cortex, and basal ganglia. These areas are responsible for detecting threats, regulating emotions, and forming habits. In individuals with OCD, these brain regions become hyperactive, causing the brain to overestimate risks or consequences. For example, a thought like, “Did I leave the stove on?” might feel catastrophic, leading to repeated checks even after confirming the stove is off.

Compulsions, such as checking, handwashing, or mental rituals, are attempts to relieve the anxiety caused by obsessions. While these behaviors provide temporary relief, they also reinforce the brain’s faulty threat-detection system. Over time, the brain learns that compulsions reduce anxiety, creating a cycle that is difficult to break. This is why stopping compulsions “cold turkey” often feels impossible—compulsions are deeply ingrained in the brain’s reward system.

Another key factor in OCD is the role of neurotransmitters, particularly serotonin. Serotonin helps regulate mood, decision-making, and behavior. In people with OCD, serotonin signaling is often disrupted, contributing to difficulties in filtering intrusive thoughts and managing emotional responses. This is one reason why selective serotonin reuptake inhibitors (SSRIs), a type of medication, are commonly prescribed for OCD. SSRIs help stabilize serotonin levels, making it easier for individuals to manage their symptoms.

Despite the neurological challenges of OCD, recovery is possible. Exposure and Response Prevention (ERP), a specialized form of cognitive-behavioral therapy, is considered the most effective treatment for OCD. ERP works by gradually exposing individuals to their fears while helping them resist the urge to perform compulsions. For instance, someone who fears contamination might practice touching a doorknob without washing their hands afterward. Over time, the brain learns that the feared outcome doesn’t occur, and the anxiety diminishes.

ERP does not change the fact that intrusive thoughts may arise, but it retrains the brain to respond differently. Combined with medication when necessary, ERP helps individuals reduce the intensity and frequency of obsessions and compulsions, allowing them to regain control over their lives.

Understanding the neurological basis of OCD highlights why treatment is essential and why compassion is so important. It is not a matter of simply “stopping”—OCD involves complex brain processes that require structured, evidence-based interventions. With the right support, individuals with OCD can learn to live full, meaningful lives beyond the constraints of their symptoms.

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